Reassembled plasma low density lipoproteins. Phospholipid-cholesterol ester-apoprotein B complexes.
نویسندگان
چکیده
منابع مشابه
A new apoprotein of human plasma very low density lipoproteins.
A new apoprotein has been isolated from delipidated human very low density lipoproteins by Sepharose 6B chromatography in 6 Y guanidine hydrochloride. This water-insoluble protein was noted to be unique to the plasma very low density and chylomicron fractions. This protein was shown to be homogeneous by urea-DEAE-cellulose chromatography, rechromatography in a guanidine-Sepharose system, sodium...
متن کاملPhospholipid/cholesteryl ester microemulsions containing unesterified cholesterol: model systems for low density lipoproteins.
As models for the effects of unesterified cholesterol (UC) on the lipid organization of low density lipoprotein (LDL), microemulsions containing either egg yolk phosphatidylcholine (EYPC) or dimyristoyl phosphatidylcholine (DMPC) as the surface component, cholesteryl oleate (CO) as the core component, and varying amounts of unesterified cholesterol were prepared by sonication. Gel filtration ch...
متن کاملCholesteryl ester transfer from phospholipid vesicles to human density lipoproteins.
The exchange of cholesteryl esters between different lipoproteins was reported to bae mediated by a protein present in human plasma. In this study wer have examined the movement of cholesteryl ester from unilamellar phospholipid vesicles to high density lipoprotein (HDL). Experimental conditions were establisehd so that vesicles containing egg yolk lecithin and cholesteryl oleatea (molar ratio ...
متن کاملApoprotein composition of very low density lipoproteins of human serum.
Methods for quantitation of the major apoproteins of human serum very low density lipoprotein have been developed employing tetramethylurea, which delipidates the lipoprotein and selectively precipitates apolipoprotein B. Six soluble apoproteins are separated by electrophoresis in polyacrylamide gel. One of these is a previously unrecognized species of R-alanine (R4-alanine), more anionic than ...
متن کاملIncreased apoprotein B in very low density lipoproteins of patients with peripheral vascular disease.
Lipoprotein compositional studies were carried out in 20 patients with atherosclerotic peripheral vascular disease. Twelve of these patients were normolipidemic, the other eight, hypertriglyceridemic. Ten normolipidemic and 10 hypertriglyceridemic age-matched subjects were used as controls. High density lipoprotein cholesterol levels were markedly reduced in the hypertriglyceridemic subjects, b...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1984
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)82194-2